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Tri-Heart® Plus (ivermectin/pyrantel) is a proven, cost-effective and easy-to-administer chewable tablet that helps keep your dog free of heartworm and also controls roundworms and hookworms. Tri-Heart Plus is a generic equivalent to Heartgard Plus, and requires a prescription from your veterinarian. It has the same active ingredients and is the same strength. Tri-Heart Plus is considered to be the #1 generic heartworm preventative recommended by veterinarians.
Dogs (6 weeks of age or older and no weight requirement)
Can cause sensitivities/allergies in herding dog breeds. Don't give your pet Tri-heart Plus if already giving a different heartworm medication. The safe use of this drug has not been evaluated in pregnant or lactating bitches.
Tri-Heart Plus (Merck)
Ivermectin/Pyrantel
Give the missed dose as soon as you remember. Do not give a double dose of the medication.
Side effects are rare, but may include lethargy, limpness, salivation, shaking, diarrhea, decreased appetite, licking lips, and belching. Higher doses in dogs may cause tremors, dilated pupils, loss of body weight, or death.
Should be stored at room temperature. Keep this medication away from children and pets.
Give Tri-Heart Plus as directed by your veterinarian. If your pet is off Tri-Heart Plus for 6 months or less, start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Do not remove the tablet from its wrapper until ready to give to your pet.
Dogs/Puppies: (6 weeks of age and older) | |
| Weight | Dosage |
| Up to 25 lbs | Give 1 chewable every month (Blue Box) |
| 26-50 lbs | Give 1 chewable every month (Green Box) |
| 51-100 lbs | Give 1 chewable every month (Brown Box) |
| Over 100 lbs | Give combination of chewables based on weight |
| Cats: |
| Do not use! |
| Horses: |
| Do not use! |
Ivermectin/Pyrantel - Blue Box (Dogs up to 25 lbs): | |
| Active Ingredients (per chewable tablet) | Amount |
| Ivermectin | 68 mcg |
| Pyrantel | 57 mcg |
Ivermectin/Pyrantel - Green Box (Dogs 26-50 lbs): | |
| Active Ingredients (per chewable tablet) | Amount |
| Ivermectin | 136 mcg |
| Pyrantel | 114 mcg |
Ivermectin/Pyrantel - Brown Box (Dogs 51-100 lbs): | |
| Active Ingredients (per chewable tablet) | Amount |
| Ivermectin | 272 mcg |
| Pyrantel | 227 mcg |
Revolution is a safe and simple monthly topical medication used to protect your pet from heartworms, fleas, and ear mites. It also protects dogs from ticks and sarcoptic mange and cats from roundworms and hookworms. Revolution for Dogs and Cats requires a prescription from your veterinarian.
Advantage Multi for is a once a month topical application that contains a combination of the insecticide (imidacloprid) and the parasiticide (moxidectin). Advantage Multi for Dogs is used for the prevention of heartworm and the treatment and control of flea infestations, hookworms, roundworms and whipworms. Advantage Multi requires a prescription from your veterinarian.
Interceptor Flavor Tabs are a palatable once-a-month tablet that prevents heartworm disease, controls adult hookworms, and removes and controls adult roundworms and whipworm infections in dogs. Interceptor for cats is an oral monthly preventative that protects against heartworms and removes adult roundworms and adult hookworms. Interceptor requires a prescription from your veterinarian.
Heartgard Plus is a real-beef Flavored chewable tablet for dogs that provides protection against heartworms, and treats and controls roundworms and hookworms. Heartgard Plus is given monthly and requires a prescription from your veterinarian.
Ivermectin/Pyrantel for dogs is a heartworm preventative that also controls roundworms and hookworms. Ivermectin/Pyrantel is a generic equivalent to Heartgard Plus, and requires a prescription from your veterinarian. Ivermectin/Pyrantel is considered to be the #1 generic heartworm preventative recommended by veterinarians.
Interceptor Plus is a monthly, broad spectrum parasiticide used to prevent heartworm disease, as well as treat and control common intestinal parasites including roundworms, hookworms, whipworms and tapeworms. Interceptor Plus offers long-lasting protection in the convenience of a tasty, easy-to-administer chewable.
Simplify your dog's heartworm and flea protection with Sentinel Spectrum, the only beef-flavored chewable to protect against 6 parasites. It is given monthly. Each chew also treats and controls whipworms, hookworms, roundworms and tapeworms. Sentinel Spectrum requires a prescription from your veterinarian
Revolution Plus for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. It kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestation.
Simparica Trio Chewable Tablets for Dogs prevents heartworms. Treats aand controls ticks (lone star ticks, black legged ticks, gulf coast ticks, american dog ticks, brown dog ticks). Treats and prevents flea infestations. Treats and controls roundworms, and adult hookworm infections.
Advantage Multi for Cats is a once-monthly topical product that controls and treats intestinal parasites like roundworm and hookworm, controls and treats ear mites, treats existing flea infestations, kills adult fleas, and prevents heartworm disease.
Bravecto Plus (Fluralaner/Moxidectin) is a Topical Spot On Solution for cats indicated for the treatment and prevention of flea and tick infestations, as well as preventing against heartworms, and the treatment of roundworms and hookworms for up to 8 weeks.
NexGard Plus (afoxolaner, moxidectin, and pyrantel chewable tablets) is the one you want for complete monthly parasite protection for your dog. It protects your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms – all in a delicious, beef-flavored, soft chew. NexGard Plus chews are safe and approved for puppies as young as 8 weeks old.
Credelio Quattro (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) is the widest parasite protection of its kind covering 6 types of parasites in one chewable tablet. It protects against ticks, fleas, heartworm disease and the three intestinal worms that can be passed to humans — tapeworms, roundworms and hookworms

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