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Comfortis (spinosad) is a fast, safe and effective treatment for flea infestations on your dog or cat. Comfortis is FDA-approved, chewable, beef-flavored tablet that kills fleas and prevents flea infestations on dogs and cats for a full month. Comfortis for Dogs & Cats requires a prescription from your veterinarian. Comfortis kills fleas before they lay eggs, and Comfortis keeps killing fleas for a full month with each dose. Use Comfortis for at least three months to treat a current flea infestation, then continue routine use to prevent a reinfestation on your pet.
Dogs & Cats (14 weeks of age or older)
Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding male dogs has not been evaluated. The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated.
Comfortis (Elanco)
Spinosad
For cats: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin.
For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures.
Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions.
Store at room temperature (68°-77° F).
Give Comfortis chewable tablets once a month with food. If vomiting occurs within 1 hour of administration, re-dose the pet with another full dose.
Dogs/Puppies: (14 weeks of age or older) | |
Weight | Dosage |
3.3-4.9 lbs (Yellow Box) | Give one 90mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
5-10 lbs (Pink Box) | Give one 140mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
10.1-20 lbs (Orange Box) | Give one 270mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
20.1-40 lbs (Green Box) | Give one 560mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
40.1-60 lbs (Blue Box) | Give one 810mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
60.1-120 lbs (Brown Box) | Give one 1620mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
Over 120 lbs | Give the appropriate combination of tablets |
Cats/Kittens: (14 weeks of age or older) | |
Weight | Dosage |
2-4 lbs (Yellow Box) | Give one 90mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
4-6 lbs (Pink Box) | Give one 140mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
6.1-12 lbs (Orange Box) | Give one 270mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
12.1-24* lbs (Green Box) | Give one 560mg chewable tablet by mouth once a month. Comfortis may be chewed, offered in food, or administered like other tablet medications |
Horses: Do not use! |
Comfortis for Dogs: 3.3-4.9 lbs - Comfortis for Cats: 2-4 lbs (Yellow Box) | |
Active Ingredient | Amount |
Spinosad | 90 mg |
Comfortis for Dogs: 5-10 lbs - Comfortis for Cats: 4-6 lbs (Pink Box) | |
Active Ingredient | Amount |
Spinosad | 140 mg |
Comfortis for Dogs 10.1-20 lbs - Comfortis for Cats: 6.1-12 lbs (Orange Box) | |
Active Ingredient | Amount |
Spinosad | 270 mg |
Comfortis for Dogs 20.1-40 lbs - Comfortis for Cats: 12.1-24 lbs (Green Box) | |
Active Ingredient | Amount |
Spinosad | 560 mg |
Comfortis for Dogs 40.1-60 lbs (Blue Box) | |
Active Ingredient | Amount |
Spinosad | 810 mg |
Comfortis for Dogs 60.1-120 lbs (Brown Box) | |
Active Ingredient | Amount |
Spinosad | 1,620 mg |
Got them off my Cat
Gave one pill to my cat along with antibiotics and within less than a week hes already starting to feel better and not scratch nearly as much as he was. Definitely going to refer this medication to anyone for fleas. For dogs and cats. About to take my dog to get them as well.
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Awesome!!
I gave my cat one pill and woke up to hundreds of dead fleas on his pillow.. He hasn't scratched one time today and running around like he was before he was taken hostage! Definitely 5 stars